Singles
Most men's titles:
7, Richard Sears (1881-87)
7, William Larned (1901-02, 1907-11)
7, Bill Tilden (1920-25, 1929)

Most consecutive men's titles:
7, Richard Sears (1881-87)

Most women's titles:
8, Molla Bjurstedt Mallory (1915-18, 1920-22, 1926)

Most consecutive women's titles:
4, Molla Bjurstedt Mallory (1915-18)
4, Helen Jacobs (1932-35)
4, Chris Evert (1975-78)

Doubles
Most men's titles:
6, Richard Sears (1882-87)
6, Holcombe Ward (1899, 1900-01, 1904-06)

Most women's titles:
13, Margaret Osborne duPont (1941-50, 1955-57)

Most titles by a men's team:
5, Richard Sears and James Dwight (1882-84, 1886-87)

Most titles by a women's team:
12, Louise Brough and Margaret Osborne duPont (1942-50, 1955-57)

Most mixed titles (men):
4, Edwin Fischer (1894-96, 1898)
4, Bill Tilden (1913-14, 1922-23)
4, Billy Talbert (1943-46)
4, Owen Davidson (1966-67, 1971, 1973)
4, Marty Riessen (1969-70, 1972, 1980)

Most mixed titles (women):
9, Margaret Osborne duPont (1943-46, 1950, 1956, 1958-60)

Most mixed titles by a team:
4, Margaret Osborne duPont and Billy Talbert (1943-46)

Overall
Most titles, all divisions (men):
16, Bill Tilden (7 singles, 5 doubles, 4 mixed)

Most titles, all divisions (women):
25, Margaret Osborne duPont (3 singles, 13 doubles, 9 mixed)

Miscellaneous
Youngest men's singles champion:
Pete Sampras, 1990 (19 years, 28 days)

Youngest women's singles champion:
Tracy Austin, 1979 (16 years, 8 months, 28 days)

Oldest men's singles champion:
William Larned, 1911 (38 years, 8 months, 3 days)

Oldest women's singles champion:
Maud Barger-Wallach, 1908 (38 years)

Most years seeded (men):
18, Jimmy Connors (1972-89)

Most years seeded (women):
19, Martina Navratilova (1975-93)

Most years seeded No. 1 (men):
5, Rod Laver (1961-62, 1968-70)
5, John McEnroe (1981-85)
5, Pete Sampras (1994, 1996-99)

Most years seeded No. 1 (women):
9, Steffi Graf (1987-91, 1993-96)

Most singles matches played, career (men):
115, Jimmy Connors (1970-89, 1991-92)

Most singles matches played, career (women):
113, Chris Evert (1971-89)